Which pharmacotherapy is commonly combined with cognitive-behavioral therapy for moderate to severe Social Anxiety Disorder?

• A. SSRIs or SNRIs.
• B. MAO inhibitors.
• C. Benzodiazepines.
• D. Antipsychotics.

Answer: (A)

SSRIs or SNRIs are commonly combined with cognitive-behavioral therapy for moderate to severe Social Anxiety Disorder because they address the underlying anxiety biology while CBT targets the thoughts and avoidance patterns driving the fear. SSRIs/SNRIs reduce core social anxiety symptoms and improve functioning, which helps a person engage more effectively in exposure and cognitive techniques during therapy. They have the strongest, most consistent evidence base and a tolerable safety profile, making them the standard pharmacotherapy to pair with CBT. MAO inhibitors are effective but rarely used due to dietary restrictions and side effects. Benzodiazepines can provide quick relief but carry dependence risks and can interfere with long-term CBT progress. Antipsychotics are not a standard treatment for this condition.